On 17 August 2022, the Ministry of Health (MoH) of the Democratic Republic of Congo (DRC) reported a confirmed case of Ebola virus disease (EVD) in the Beni district of North Kivu province. This case was confirmed six weeks after the most recent EVD outbreak in Equateur province was declared over on 4 July 2022. It is the third EVD outbreak declared in the North Kivu province since 2018. Results from genome sequencing revealed that the current outbreak is linked to the 2018 – 2020 EVD outbreak that occurred in the North Kivu province of DRC and may not represent any new spillover event. The patient was a 46-year-old female who presented with a persistent cough, headache, polyarthralgia and intense fatigue to the Beni General Reference Hospital on 23 July 2022. She was admitted to the hospital the same day, and following a 23-day hospitalisation, the patient died on 15 August 2022 due to multiple organ failure. A post-mortem oropharyngeal sample collected from the patient on the same day tested positive for EVD at the Institut National de Recherche Biomédicale (INRB) Beni mobile laboratory using the Cepheid Xpert Ebola assay. On 16 August 2022, second-level confirmation of the sample was done at the Rodolphe Mérieux INRB-Goma laboratory using the polymerase chain reaction.